MICAL1 抗体
Quick Overview for MICAL1 抗体 (ABIN7116285)
抗原
See all MICAL1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- MICAL1 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- microtubule associated monoxygenase, calponin and LIM domain containing 1
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亚型
- IgG
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应用备注
- WB: 1:1000-1:4000, IP: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:50-1:500
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- MICAL1 (Microtubule Associated Monoxygenase, Calponin and LIM Domain Containing 1 (MICAL1))
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别名
- MICAL1
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背景
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Synonyms: [F-actin]-monooxygenase MICAL1|Molecule interacting with CasL protein 1 (MICAL-1)|NEDD9-interacting protein with calponin homology and LIM domains|MICAL1|MICAL|NICAL
Background: Monooxygenase that promotes depolymerization of F-actin by mediating oxidation of specific methionine residues on actin. Acts by modifying actin subunits through the addition of oxygen to form methionine-sulfoxide, leading to promote actin filament severing and prevent repolymerization(Probable). Acts as a cytoskeletal regulator that connects NEDD9 to intermediate filaments. Also acts as a negative regulator of apoptosis via its interaction with STK38 and STK38L, acts by antagonizing STK38 and STK38L activation by MST1/STK4.
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分子量
- 120 kDa
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基因ID
- 64780
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UniProt
- Q8TDZ2
抗原
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