MME 抗体
Quick Overview for MME 抗体 (ABIN7116192)
抗原
See all MME 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- MME antibody
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纯化方法
- Protein A+G purification
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- membrane metallo-endopeptidase
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亚型
- IgG2a
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应用备注
- WB: 1:500-1:5000, IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- MME (Membrane Metallo-Endopeptidase (MME))
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别名
- MME
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背景
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Synonyms: Neprilysin|Atriopeptidase|Common acute lymphocytic leukemia antigen (CALLA)|Enkephalinase|Neutral endopeptidase 24.11 (NEP, Neutral endopeptidase)|Skin fibroblast elastase (SFE)|MME|EPN
Background: MME is also names as neprilysin,CALLA,NEP,SFE,CD10 and belongs to the peptidase M13 family.It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium.CD10 has been considered a useful marker in the diagnosis of renal carcinomas, because of its expression in clear cell and papillary renal cell carcinomas and its absence in chromophobe renal cell carcinomas(PMID:15286660).This antibody is specific to MME.
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分子量
- 90-110 kDa
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基因ID
- 4311
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UniProt
- P08473
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途径
- RTK signaling, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration
抗原
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