MIA3 抗体
Quick Overview for MIA3 抗体 (ABIN7116180)
抗原
See all MIA3 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- MIA3 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- melanoma inhibitory activity family, member 3
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亚型
- IgG
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anti-Melanoma Inhibitory Activity Family, Member 3 (MIA3) (AA 1-120) antibody
MIA3 适用: 人 WB, IHC (p), ICC, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Melanoma Inhibitory Activity Family, Member 3 (MIA3) (N-Term) antibodyMIA3 适用: 人 WB, IHC (p), ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Melanoma Inhibitory Activity Family, Member 3 (MIA3) (C-Term) antibodyMIA3 适用: 人, 小鼠, 大鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:2000, IP: 1:200-1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- MIA3 (Melanoma Inhibitory Activity Family, Member 3 (MIA3))
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别名
- MIA3
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背景
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Synonyms: Transport and Golgi organization protein 1 homolog (TANGO1)|C219-reactive peptide|D320|Melanoma inhibitory activity protein 3|MIA3|KIAA0268|TANGO
Background: Plays a role in the transport of cargos that are too large to fit into COPII-coated vesicles and require specific mechanisms to be incorporated into membrane-bound carriers and exported from the endoplasmic reticulum. This protein is required for collagen VII(COL7A1) secretion by loading COL7A1 into transport carriers. It may participate in cargo loading of COL7A1 at endoplasmic reticulum exit sites by binding to COPII coat subunits Sec23/24 and guiding SH3-bound COL7A1 into a growing carrier. Does not play a role in global protein secretion and is apparently specific to COL7A1 cargo loading. However, it may participate in secretion of other proteins in cells that do not secrete COL7A1. It is also specifically required for the secretion of lipoproteins by participating in their export from the endoplasmic reticulum(PubMed:27138255).
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分子量
- 250-300 kDa
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基因ID
- 375056
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UniProt
- Q5JRA6
抗原
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