MSL1 抗体 (AA 473-614)
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Quick Overview for MSL1 抗体 (AA 473-614) (ABIN7116032)
抗原
See all MSL1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 473-614
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原理
- MSL1 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
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Immunogen sequence: 473-614aa
Immunogen: male-specific lethal 1 homolog(Drosophila)
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亚型
- IgG
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anti-Male-Specific Lethal 1 Homolog (MSL1) (AA 210-300) antibody
MSL1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Male-Specific Lethal 1 Homolog (MSL1) (Middle Region) antibodyMSL1 适用: 人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- MSL1 (Male-Specific Lethal 1 Homolog (MSL1))
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别名
- MSL1
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背景
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Synonyms: Male-specific lethal 1 homolog (MSL-1)|Male-specific lethal 1-like 1 (MSL1-like 1)|Male-specific lethal-1 homolog 1|MSL1|MSL1L1
Background: Component of histone acetyltransferase complex responsible for the majority of histone H4 acetylation at 'Lys-16'(H4K16ac) which is implicated in the formation of higher-order chromatin structure. Greatly enhances MSL2 E3 ubiquitin ligase activity, promoting monoubiquitination of histone H2B at 'Lys-34'(H2BK34Ub). This modification in turn stimulates histone H3 methylation at 'Lys-4'(H3K4me) and 'Lys-79'(H3K79me) and leads to gene activation, including that of HOXA9 and MEIS1. In the MSL complex, acts as a scaffold to tether MSL3 and KAT8 together for enzymatic activity regulation.
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分子量
- 67 kDa
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基因ID
- 339287
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UniProt
- Q68DK7
抗原
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