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- 抗原 See all MSL1 抗体
- MSL1 (Male-Specific Lethal 1 Homolog (MSL1))
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抗原表位
- AA 210-300
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MSL1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 原理
- MSL1 Rabbit pAb
- 序列
- LAVPSWRDHS VEPLRDPNPS DLLENLDDSV FSKRHAKLEL DEKRRKRWDI QRIREQRILQ RLQLRMYKKK GIQESEPEVT SFFPEPDDVE S
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Polyclonal Antibodies
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 210-300 of human MSL1 (NP_001012241).
- 亚型
- IgG
- Top Product
- Discover our top product MSL1 Primary Antibody
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anti-Male-Specific Lethal 1 Homolog (MSL1) antibody
MSL1 适用: 人 IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB,1:500 - 1:2000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- MSL1 (Male-Specific Lethal 1 Homolog (MSL1))
- 别名
- MSL1 (MSL1 产品)
- 别名
- MSL-1 antibody, hMSL1 antibody, 2810017F12Rik antibody, 4121402D02Rik antibody, 4930463F05Rik antibody, AA682082 antibody, Msl-1 antibody, male specific lethal 1 homolog antibody, male-specific lethal 1 homolog (Drosophila) antibody, MSL1 antibody, Msl1 antibody
- 背景
- Component of histone acetyltransferase complex responsible for the majority of histone H4 acetylation at 'Lys-16' (H4K16ac which is implicated in the formation of higher-order chromatin structure. Greatly enhances MSL2 E3 ubiquitin ligase activity, promoting monoubiquitination of histone H2B at 'Lys-34' (H2BK34Ub. This modification in turn stimulates histone H3 methylation at 'Lys-4' (H3K4me and 'Lys-79' (H3K79me and leads to gene activation, including that of HOXA9 and MEIS1. In the MSL complex, acts as a scaffold to tether MSL3 and KAT8 together for enzymatic activity regulation.,MSL-1,hMSL1,MSL1,Epigenetics & Nuclear Signaling,Histones,MSL1
- 基因ID
- 339287
- UniProt
- Q68DK7
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