MIF 抗体
Quick Overview for MIF 抗体 (ABIN7115996)
抗原
See all MIF 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- MIF antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- macrophage migration inhibitory factor(glycosylation-inhibiting factor)
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000, IP: 1:500-1:2000, IHC: 1:50-1:500, IF: 1:50-1:500
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- MIF (Macrophage Migration Inhibitory Factor (Glycosylation-Inhibiting Factor) (MIF))
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别名
- MIF
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背景
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Synonyms: Macrophage migration inhibitory factor (MIF)|Glycosylation-inhibiting factor (GIF)|L-dopachrome isomerase|L-dopachrome tautomerase|Phenylpyruvate tautomerase|MIF|GLIF|MMIF
Background: Pro-inflammatory cytokine. Involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity(in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity.
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分子量
- 12 kDa
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基因ID
- 4282
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UniProt
- P14174
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途径
- Regulation of Systemic Arterial Blood Pressure by Hormones, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling
抗原
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