LRP5 抗体 (AA 1408-1615)
Quick Overview for LRP5 抗体 (AA 1408-1615) (ABIN7115919)
抗原
See all LRP5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1408-1615
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原理
- LRP5 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
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Immunogen sequence: 1408-1615aa
Immunogen: low density lipoprotein receptor-related protein 5
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亚型
- IgG
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应用备注
- WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- LRP5 (Low Density Lipoprotein Receptor-Related Protein 5 (LRP5))
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别名
- LRP5
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背景
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Synonyms: Low-density lipoprotein receptor-related protein 5 (LRP-5)|Low-density lipoprotein receptor-related protein 7 (LRP-7)|LRP5|LR3|LRP7
Background: This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy. Alternative splicing results in multiple transcript variants.
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分子量
- 180 kDa
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基因ID
- 4041
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UniProt
- O75197
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途径
- WNT signaling, Stem Cell Maintenance, Positive Regulation of fat Cell Differentiation
抗原
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