LARP1 抗体
Quick Overview for LARP1 抗体 (ABIN7115745)
抗原
See all LARP1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- LARP1 antibody
-
纯化方法
- Immunogen affinity purified
-
纯度
- ≥95 % as determined by SDS-PAGE
-
免疫原
- La ribonucleoprotein domain family, member 1
-
亚型
- IgG
-
-
-
-
应用备注
- WB: 1:500-1:2000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze / thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- -20°C for 12 months
-
有效期
- 12 months
-
-
- LARP1 (La Ribonucleoprotein Domain Family, Member 1 (LARP1))
-
别名
- LARP1
-
背景
-
Synonyms: La-related protein 1|La ribonucleoprotein domain family member 1|LARP1|KIAA0731|LARP
Background: RNA-binding protein that promotes translation of specific classes of mRNAs downstream of the mTORC1 complex. Associates with the mRNA 5'cap in an MTOR-dependent manner and associates with mRNAs containing a 5' terminal oligopyrimidine(5'TOP) motif, which is present in mRNAs encoding for ribosomal proteins and several components of the translation machinery. Associates with actively translating ribosomes via interaction with PABPC1/PABP and stimulates translation of mRNAs containing a 5'TOP, thereby regulating cell growth and proliferation. Positively regulates the replication of dengue virus(DENV)(PubMed:26735137).
-
分子量
- 140-150 kDa
-
基因ID
- 23367
-
UniProt
- Q6PKG0
-
途径
- SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
抗原
-