KNG1 抗体
Quick Overview for KNG1 抗体 (ABIN7115720)
抗原
See all KNG1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- KNG1 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- Kininogen-1
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000, IF: 1:50-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- KNG1 (Kininogen 1 (KNG1))
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别名
- KNG1
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背景
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Synonyms: Kininogen-1|Alpha-2-thiol proteinase inhibitor|Fitzgerald factor|High molecular weight kininogen (HMWK)|Williams-Fitzgerald-Flaujeac factor|Kininogen-1 heavy chain|T-kinin Alternative names: Ile-Ser-Bradykinin|Bradykinin Alternative names: Kallidin I|Lysyl-bradykinin Alternative names: Kallidin II|Kininogen-1 light chain|Low molecular weight growth-promoting factor|KNG1|BDK|KNG
Background: This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. Bradykinin also functions as an antimicrobial peptide with antibacterial and antifungal activity. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.
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分子量
- 68 kDa
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基因ID
- 3827
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UniProt
- P01042
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途径
- ACE Inhibitor Pathway, Glycosaminoglycan Metabolic Process
抗原
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