KIF7 抗体
Quick Overview for KIF7 抗体 (ABIN7115710)
抗原
See all KIF7 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- kinesin family member 7
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亚型
- IgG
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anti-Kinesin Family Member 7 (KIF7) antibody
KIF7 适用: 人, 小鼠, 大鼠 IHC (p), IF 宿主: 小鼠 Monoclonal 3I4 unconjugated
anti-Kinesin Family Member 7 (KIF7) antibodyKIF7 适用: 人, 小鼠, 大鼠 WB, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Kinesin Family Member 7 (KIF7) antibodyKIF7 适用: 人 ELISA, IHC 宿主: 小鼠 Monoclonal unconjugated
anti-Kinesin Family Member 7 (KIF7) antibodyKIF7 适用: 人, 小鼠, 大鼠 IHC 宿主: 小鼠 Monoclonal 3F8 unconjugated
anti-Kinesin Family Member 7 (KIF7) (AA 1224-1273) antibodyKIF7 适用: 人, Cow, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Kinesin Family Member 7 (KIF7) (AA 1044-1343) antibodyKIF7 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:2000, IP: 1:500-1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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有效期
- 12 months
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- KIF7 (Kinesin Family Member 7 (KIF7))
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别名
- KIF7
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背景
- Synonyms:KIF7, kinesin family member 7, Kinesin like protein KIF7, UNQ340 Background:Essential for hedgehog signaling regulation: acts as both a negative and positive regulator of sonic hedgehog(Shh) and Indian hedgehog(Ihh) pathways, acting downstream of SMO, through both SUFU-dependent and-independent mechanisms(PubMed:21633164). Involved in the regulation of microtubular dynamics. Required for proper organization of the ciliary tip and control of ciliary localization of SUFU-GLI2 complexes(By similarity). Required for localization of GLI3 to cilia in response to Shh. Negatively regulates Shh signaling by preventing inappropriate activation of the transcriptional activator GLI2 in the absence of ligand. Positively regulates Shh signaling by preventing the processing of the transcription factor GLI3 into its repressor form. In keratinocytes, promotes the dissociation of SUFU-GLI2 complexes, GLI2 nuclear translocation and Shh signaling activation(By similarity). Involved in the regulation of epidermal differentiation and chondrocyte development(By similarity).
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分子量
- 150 kDa
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基因ID
- 374654
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UniProt
- Q2M1P5
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途径
- Hedgehog Signaling
抗原
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