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Cytokeratin 18 抗体 (AA 127-430)

This anti-Cytokeratin 18 antibody is a 小鼠 单克隆 antibody detecting Cytokeratin 18 in WB, IHC, IF, FACS 和 ELISA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7115628
发货至: 中国
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北京 101111
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Cytokeratin 18 抗体 (AA 127-430) (ABIN7115628)

抗原

See all Cytokeratin 18 (KRT18) 抗体
Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))

适用

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人, 小鼠, 大鼠

宿主

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小鼠

克隆类型

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单克隆

标记

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This Cytokeratin 18 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), ELISA

克隆位点

6E3
  • 抗原表位

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    AA 127-430

    原理

    KRT18 antibody

    纯化方法

    Protein A+G purification

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    Immunogen sequence: 127-430aa

    Immunogen: keratin 18

    亚型

    IgG2a
  • 应用备注

    WB: 1:5000-1:30000, IHC: 1:500-1:1000, IF: 1:100-1:300

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))

    别名

    KRT18

    背景

    Synonyms: Keratin, type I cytoskeletal 18|Cell proliferation-inducing gene 46 protein|Cytokeratin-18 (CK-18)|Keratin-18 (K18)|KRT18|CYK18

    Background: Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells, which are classified into two major sequence types. Type I keratins are a group of acidic intermediate filament proteins, including K9-K23, and the hair keratins Ha1-Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins, including K1-K8, and the hair keratins, Hb1-Hb6. KRT18, also named as CYK18, PIG46 and K18, is the most commonly found members of the intermediate filament gene family. KRT18 is a type I keratin which is found primarily in non squamous epithelia and is present in a majority of adenocarcinomas and ductal carcinomas but not in squamous cell carcinomas.

    分子量

    48 kDa

    基因ID

    3875

    UniProt

    P05783

    途径

    Apoptosis, Caspase Cascade in Apoptosis
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