IREB2 抗体
Quick Overview for IREB2 抗体 (ABIN7115514)
抗原
See all IREB2 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- IREB2 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- iron-responsive element binding protein 2
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000, IF: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- IREB2 (Iron-Responsive Element Binding Protein 2 (IREB2))
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别名
- IREB2
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背景
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Synonyms: Iron-responsive element-binding protein 2 (IRE-BP 2)|Iron regulatory protein 2 (IRP2)|IREB2
Background: RNA-binding protein that binds to iron-responsive elements(IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. Binding to the IRE element in ferritin results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.
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分子量
- 90-105 kDa
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基因ID
- 3658
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UniProt
- P48200
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途径
- Transition Metal Ion Homeostasis
抗原
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