IL23A 抗体 (AA 20-189)
Quick Overview for IL23A 抗体 (AA 20-189) (ABIN7115450)
抗原
See all IL23A 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 20-189
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原理
- IL23A antibody
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纯化方法
- Protein A+G purification
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
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Immunogen sequence: 20-189aa
Immunogen: interleukin 23, alpha subunit p19
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亚型
- IgG1
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应用备注
- WB: 1:500-1:2000, IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- IL23A (Interleukin 23, alpha subunit p19 (IL23A))
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别名
- IL23A
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背景
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Synonyms: Interleukin-23 subunit alpha (IL-23 subunit alpha, IL-23-A)|Interleukin-23 subunit p19 (IL-23p19)|IL23A|SGRF
Background: Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.
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分子量
- 21 kDa
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基因ID
- 51561
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UniProt
- Q9NPF7
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
抗原
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