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Interleukin 17a 抗体 (AA 1-155)

This 小鼠 单克隆 anti-Interleukin 17a antibody (Clone 5E2) specifically detects Interleukin 17a in ELISA, WB 和 FACS. The antibody is reactive with 人 samples.
产品编号 ABIN7115424
发货至: 中国
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北京 101111
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Quick Overview for Interleukin 17a 抗体 (AA 1-155) (ABIN7115424)

抗原

See all Interleukin 17a (IL17A) 抗体
Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

适用

  • 103
  • 56
  • 19
  • 7
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  • 4
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  • 3
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  • 3

宿主

  • 60
  • 53
  • 20
  • 15
  • 5
  • 2
小鼠

克隆类型

  • 89
  • 65
  • 1
单克隆

标记

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  • 1
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This Interleukin 17a antibody is un-conjugated

应用范围

  • 71
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  • 41
  • 18
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  • 11
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  • 5
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  • 1
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  • 1
  • 1
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  • 1
ELISA, Western Blotting (WB), Flow Cytometry (FACS)

克隆位点

5E2
  • 抗原表位

    • 7
    • 6
    • 6
    • 5
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    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
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    AA 1-155

    原理

    IL17A antibody

    纯化方法

    Protein A+G purification

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    Immunogen sequence: 1-155aa

    Immunogen: interleukin 17A

    亚型

    IgG1
  • 应用备注

    WB: 1:500-1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

    别名

    IL17A

    背景

    Synonyms: Interleukin-17A (IL-17, IL-17A)|Cytotoxic T-lymphocyte-associated antigen 8 (CTLA-8)|IL17A|CTLA8|IL17

    Background: IL17A, also named as IL-17, is a proinflammatory cytokine. IL-17, synthesized only by memory T cells and natural killer cells, has pleiotropic effects, mainly in the recruitment and activation of neutrophils. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2(PTGS2/COX-2), as well as enhance the production of nitric oxide(NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. The IL-17 receptor is a type I transmembrane protein, that is widely expressed on epithelial cells, fibroblasts, B and T cells, and monocytic cells. In psoriatic skin lesions, both Th17 cells and their downstream effector molecules, e.g. IL-17 and IL-22, are highly increased.

    分子量

    18 kDa

    基因ID

    3605

    UniProt

    Q16552
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