电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

IFITM3 抗体

This anti-IFITM3 antibody is a 小鼠 单克隆 antibody detecting IFITM3 in WB, ELISA, IHC, IF 和 FACS. Suitable for 人.
产品编号 ABIN7115388
发货至: 中国

Quick Overview for IFITM3 抗体 (ABIN7115388)

抗原

See all IFITM3 抗体
IFITM3 (Interferon-Induced Transmembrane Protein 3 (IFITM3))

适用

  • 39
  • 6
  • 5
  • 1
  • 1
  • 1
  • 1

宿主

  • 32
  • 5
  • 3
小鼠

克隆类型

  • 34
  • 6
单克隆

标记

  • 28
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This IFITM3 antibody is un-conjugated

应用范围

  • 30
  • 19
  • 13
  • 12
  • 8
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

克隆位点

5H4
  • 纯化方法

    Protein A+G purification

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    IFITM2/3 fusion protein

    亚型

    IgG1
  • 应用备注

    WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:10-1:100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    IFITM3 (Interferon-Induced Transmembrane Protein 3 (IFITM3))

    别名

    IFITM3

    背景

    Synonyms:1 8U, IFITM3, IP15 Background:IFN-induced antiviral protein which disrupts intracellular cholesterol homeostasis. Inhibits the entry of viruses to the host cell cytoplasm by preventing viral fusion with cholesterol depleted endosomes. May inactivate new enveloped viruses which buds out of the infected cell, by letting them go out with a cholesterol depleted membrane. Active against multiple viruses, including influenza A virus, SARS coronavirus(SARS-CoV), Marburg virus(MARV) and Ebola virus(EBOV), Dengue virus(DNV), West Nile virus(WNV), human immunodeficiency virus type 1(HIV-1) and vesicular stomatitis virus(VSV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry, SARS-CoV S protein-mediated viral entry and VSV G protein-mediated viral entry. Plays a critical role in the structural stability and function of vacuolar ATPase(v-ATPase). Establishes physical contact with the v-ATPase of endosomes which is critical for proper clathrin localization and is also required for the function of the v-ATPase to lower the pH in phagocytic endosomes thus establishing an antiviral state.This antibody recognizes both IFITM2 and IFITM3.

    分子量

    14 kDa

    基因ID

    10410

    UniProt

    Q01628
You are here:
Chat with us!