IFITM3 抗体 (AA 1-133)
Quick Overview for IFITM3 抗体 (AA 1-133) (ABIN7115388)
抗原
See all IFITM3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-133
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原理
- IFITM3 antibody
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纯化方法
- Protein A+G purification
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
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Immunogen sequence: 1-133aa
Immunogen: IFITM2/3 fusion protein
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亚型
- IgG1
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anti-Interferon-Induced Transmembrane Protein 3 (IFITM3) (AA 1-133) antibody
IFITM3 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Interferon-Induced Transmembrane Protein 3 (IFITM3) (AA 1-133) antibodyIFITM3 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Interferon-Induced Transmembrane Protein 3 (IFITM3) (AA 1-30), (N-Term) antibodyIFITM3 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB13975 unconjugated
anti-Interferon-Induced Transmembrane Protein 3 (IFITM3) (AA 1-133) antibodyIFITM3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4C8-1B10 unconjugated
anti-Interferon-Induced Transmembrane Protein 3 (IFITM3) (AA 1-133) antibodyIFITM3 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 2H4-1D5 unconjugated
anti-Interferon-Induced Transmembrane Protein 3 (IFITM3) (AA 1-57) antibodyIFITM3 适用: 人 WB, ELISA, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Interferon-Induced Transmembrane Protein 3 (IFITM3) (Internal Region) antibodyVerified IFITM3 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Interferon-Induced Transmembrane Protein 3 (IFITM3) (AA 1-133) antibodyIFITM3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Interferon-Induced Transmembrane Protein 3 (IFITM3) (N-Term) antibodyIFITM3 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Interferon-Induced Transmembrane Protein 3 (IFITM3) (N-Term) antibodyVerified IFITM3 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:10-1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- IFITM3 (Interferon-Induced Transmembrane Protein 3 (IFITM3))
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别名
- IFITM3
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背景
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Synonyms: Interferon-induced transmembrane protein 3|Dispanin subfamily A member 2b (DSPA2b)|Interferon-inducible protein 1-8U|IFITM3
Background: IFN-induced antiviral protein which disrupts intracellular cholesterol homeostasis. Inhibits the entry of viruses to the host cell cytoplasm by preventing viral fusion with cholesterol depleted endosomes. May inactivate new enveloped viruses which buds out of the infected cell, by letting them go out with a cholesterol depleted membrane. Active against multiple viruses, including influenza A virus, SARS coronavirus(SARS-CoV), Marburg virus(MARV) and Ebola virus(EBOV), Dengue virus(DNV), West Nile virus(WNV), human immunodeficiency virus type 1(HIV-1) and vesicular stomatitis virus(VSV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry, SARS-CoV S protein-mediated viral entry and VSV G protein-mediated viral entry. Plays a critical role in the structural stability and function of vacuolar ATPase(v-ATPase). Establishes physical contact with the v-ATPase of endosomes which is critical for proper clathrin localization and is also required for the function of the v-ATPase to lower the pH in phagocytic endosomes thus establishing an antiviral state.This antibody recognizes both IFITM2 and IFITM3.
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分子量
- 14 kDa
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基因ID
- 10410
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UniProt
- Q01628
抗原
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