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IFITM3 抗体

IFITM3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, IP, FACS 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7115387
发货至: 中国
  • 抗原 See all IFITM3 抗体
    IFITM3 (Interferon-Induced Transmembrane Protein 3 (IFITM3))
    适用
    • 36
    • 5
    • 4
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 27
    • 6
    • 3
    克隆类型
    • 32
    • 4
    多克隆
    标记
    • 24
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IFITM3 antibody is un-conjugated
    应用范围
    • 26
    • 18
    • 9
    • 9
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Flow Cytometry (FACS)
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    interferon induced transmembrane protein 3
    亚型
    IgG
    Top Product
    Discover our top product IFITM3 Primary Antibody
  • 应用备注
    WB: 1:500-1:2000, IP: 1:500-1:3000, IHC: 1:50-1:400, IF: 1:50-1:500
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    IFITM3 (Interferon-Induced Transmembrane Protein 3 (IFITM3))
    别名
    IFITM3 (IFITM3 产品)
    别名
    1110004C05Rik antibody, Cd225 antibody, Cdw217 antibody, DSPA2b antibody, Fgls antibody, IP15 antibody, mil-1 antibody, 1-8U antibody, rat8 antibody, Interferon-induced transmembrane protein 3 antibody, interferon induced transmembrane protein 3 antibody, ifm3 antibody, Ifitm3 antibody, IFITM3 antibody
    背景
    Synonyms:1 8U, IFITM3, IP15 Background:IFN-induced antiviral protein which disrupts intracellular cholesterol homeostasis. Inhibits the entry of viruses to the host cell cytoplasm by preventing viral fusion with cholesterol depleted endosomes. May inactivate new enveloped viruses which buds out of the infected cell, by letting them go out with a cholesterol depleted membrane. Active against multiple viruses, including influenza A virus, SARS coronavirus(SARS-CoV), Marburg virus(MARV) and Ebola virus(EBOV), Dengue virus(DNV), West Nile virus(WNV), human immunodeficiency virus type 1(HIV-1) and vesicular stomatitis virus(VSV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry, SARS-CoV S protein-mediated viral entry and VSV G protein-mediated viral entry. Plays a critical role in the structural stability and function of vacuolar ATPase(v-ATPase). Establishes physical contact with the v-ATPase of endosomes which is critical for proper clathrin localization and is also required for the function of the v-ATPase to lower the pH in phagocytic endosomes thus establishing an antiviral state.
    分子量
    14 kDa
    基因ID
    10410
    UniProt
    Q01628
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