电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

ING4 抗体

This anti-ING4 antibody is a 兔 多克隆 antibody detecting ING4 in WB, ELISA, IHC, IP 和 IF. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7115237
发货至: 中国

Quick Overview for ING4 抗体 (ABIN7115237)

抗原

See all ING4 抗体
ING4 (Inhibitor of Growth Family, Member 4 (ING4))

适用

  • 30
  • 16
  • 12
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 26
  • 3
  • 1

克隆类型

  • 29
  • 1
多克隆

标记

  • 19
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This ING4 antibody is un-conjugated

应用范围

  • 18
  • 12
  • 6
  • 5
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)
  • 纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    inhibitor of growth family, member 4

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200, IP: 1:200-1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    ING4 (Inhibitor of Growth Family, Member 4 (ING4))

    别名

    ING4

    背景

    Synonyms:ING4, Inhibitor of growth protein 4, my036, P29ing4 Background:Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Through chromatin acetylation it may function in DNA replication. May inhibit tumor progression by modulating the transcriptional output of signaling pathways which regulate cell proliferation. Can suppress brain tumor angiogenesis through transcriptional repression of RELA/NFKB3 target genes when complexed with RELA. May also specifically suppress loss of contact inhibition elicited by activated oncogenes such as MYC. Represses hypoxia inducible factor's(HIF) activity by interacting with HIF prolyl hydroxylase 2(EGLN1). Can enhance aopotosis induced by serum starvation in mammary epithelial cell line HC11(By similarity).

    分子量

    29kd

    基因ID

    51147

    UniProt

    Q9UNL4
You are here:
Chat with us!