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IDO1 抗体

This anti-IDO1 antibody is a 兔 多克隆 antibody detecting IDO1 in WB, ELISA 和 IHC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7115217
发货至: 中国

Quick Overview for IDO1 抗体 (ABIN7115217)

抗原

See all IDO1 抗体
IDO1 (Indoleamine 2,3-Dioxygenase 1 (IDO1))

适用

  • 83
  • 31
  • 16
  • 8
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 77
  • 16
  • 1
  • 1

克隆类型

  • 68
  • 27
  • 1
多克隆

标记

  • 67
  • 5
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This IDO1 antibody is un-conjugated

应用范围

  • 74
  • 36
  • 36
  • 23
  • 17
  • 16
  • 15
  • 14
  • 12
  • 12
  • 6
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    indoleamine 2,3-dioxygenase 1

    亚型

    IgG
  • 应用备注

    WB: 1:1000-1:4000, IHC: 1:50-1:500

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    IDO1 (Indoleamine 2,3-Dioxygenase 1 (IDO1))

    别名

    IDO1

    背景

    Synonyms:CD107B, IDO, IDO 1, IDO1, INDO, indoleamine 2,3 dioxygenase 1 Background:Catalyzes the first and rate limiting step of the catabolism of the essential amino acid tryptophan along the kynurenine pathway(PubMed:17671174). Involved in the peripheral immune tolerance, contributing to maintain homeostasis by preventing autoimmunity or immunopathology that would result from uncontrolled and overreacting immune responses(PubMed:25691885). Tryptophan shortage inhibits T lymphocytes division and accumulation of tryptophan catabolites induces T-cell apoptosis and differentiation of regulatory T-cells(PubMed:25691885). Acts as a suppressor of anti-tumor immunity(PubMed:23103127, PubMed:25157255, PubMed:14502282, PubMed:25691885). Limits the growth of intracellular pathogens by depriving tryptophan(PubMed:25691885). Protects the fetus from maternal immune rejection(PubMed:25691885).

    分子量

    42 kDa

    基因ID

    3620

    UniProt

    P14902

    途径

    Activated T Cell Proliferation
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