IDO1 抗体 (AA 1-403)
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北京 101111
Quick Overview for IDO1 抗体 (AA 1-403) (ABIN7115217)
抗原
See all IDO1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-403
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原理
- IDO1 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
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Immunogen sequence: 1-403aa,full length
Immunogen: indoleamine 2,3-dioxygenase 1
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亚型
- IgG
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anti-Indoleamine 2,3-Dioxygenase 1 (IDO1) (Internal Region) antibody
Verified IDO1 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Indoleamine 2,3-Dioxygenase 1 (IDO1) (AA 1-403) antibodyIDO1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 4D2 unconjugated
anti-Indoleamine 2,3-Dioxygenase 1 (IDO1) antibodyIDO1 适用: 人 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 1E11 unconjugated
anti-Indoleamine 2,3-Dioxygenase 1 (IDO1) (AA 1-403) antibodyIDO1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Indoleamine 2,3-Dioxygenase 1 (IDO1) antibodyIDO1 适用: 小鼠 WB, ELISA, IHC, IF, FACS, IP, FM, MA 宿主: 小鼠 Monoclonal 2E2-6 unconjugated
anti-Indoleamine 2,3-Dioxygenase 1 (IDO1) (AA 1-100) antibodyIDO1 适用: 人, 小鼠 ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Indoleamine 2,3-Dioxygenase 1 (IDO1) (AA 204-403) antibodyIDO1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Indoleamine 2,3-Dioxygenase 1 (IDO1) (Internal Region) antibodyIDO1 适用: 人, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Indoleamine 2,3-Dioxygenase 1 (IDO1) (AA 304-403) antibodyIDO1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1C5 unconjugated
anti-Indoleamine 2,3-Dioxygenase 1 (IDO1) antibodyIDO1 适用: 小鼠 WB, ELISA, IHC, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000-1:4000, IHC: 1:50-1:500
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- IDO1 (Indoleamine 2,3-Dioxygenase 1 (IDO1))
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别名
- IDO1
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背景
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Synonyms: Indoleamine 2,3-dioxygenase 1 (IDO-1)|Indoleamine-pyrrole 2,3-dioxygenase|IDO1|IDO|INDO
Background: Catalyzes the first and rate limiting step of the catabolism of the essential amino acid tryptophan along the kynurenine pathway(PubMed:17671174). Involved in the peripheral immune tolerance, contributing to maintain homeostasis by preventing autoimmunity or immunopathology that would result from uncontrolled and overreacting immune responses(PubMed:25691885). Tryptophan shortage inhibits T lymphocytes division and accumulation of tryptophan catabolites induces T-cell apoptosis and differentiation of regulatory T-cells(PubMed:25691885). Acts as a suppressor of anti-tumor immunity(PubMed:23103127, PubMed:25157255, PubMed:14502282, PubMed:25691885). Limits the growth of intracellular pathogens by depriving tryptophan(PubMed:25691885). Protects the fetus from maternal immune rejection(PubMed:25691885).
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分子量
- 42 kDa
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基因ID
- 3620
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UniProt
- P14902
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途径
- Activated T Cell Proliferation
抗原
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