Importin 9 抗体
Quick Overview for Importin 9 抗体 (ABIN7115211)
抗原
See all Importin 9 (IPO9) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- RANBP9 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- RAN binding protein 9
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- Importin 9 (IPO9)
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别名
- RANBP9
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背景
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Synonyms: Ran-binding protein 9 (RanBP9)|BPM-L|BPM90|Ran-binding protein M (RanBPM)|RanBP7|RANBP9|RANBPM
Background: May act as an adapter protein to couple membrane receptors to intracellular signaling pathways. May be involved in signaling of ITGB2/LFA-1 and other integrins. Enhances HGF-MET signaling by recruiting Sos and activating the Ras pathway. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but not affect estrogen-induced transactivation. Stabilizes TP73 isoform Alpha, probably by inhibiting its ubiquitination, and increases its proapoptotic activity. Inhibits the kinase activity of DYRK1A and DYRK1B. Inhibits FMR1 binding to RNA(By similarity).
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分子量
- 80-90 kDa
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基因ID
- 10048
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UniProt
- Q96S59
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途径
- Protein targeting to Nucleus
抗原
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