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HUS1 抗体

This anti-HUS1 antibody is a 兔 多克隆 antibody detecting HUS1 in WB, ELISA 和 IHC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7115125
发货至: 中国

Quick Overview for HUS1 抗体 (ABIN7115125)

抗原

See all HUS1 抗体
HUS1 (HUS1 Checkpoint Homolog (S. Pombe) (HUS1))

适用

人, 小鼠, 大鼠

宿主

  • 52
  • 4

克隆类型

  • 55
  • 1
多克隆

标记

  • 25
  • 4
  • 4
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This HUS1 antibody is un-conjugated

应用范围

  • 28
  • 23
  • 13
  • 13
  • 11
  • 10
  • 4
  • 4
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    HUS1 checkpoint homolog (S. pombe)

    亚型

    IgG
  • 应用备注

    WB: 1:500 - 1:2000, IHC: 1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3 ,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    HUS1 (HUS1 Checkpoint Homolog (S. Pombe) (HUS1))

    别名

    HUS1

    背景

    Synonyms: Background:The protein encoded by this gene is a component of an evolutionarily conserved, genotoxin-activated checkpoint complex that is involved in the cell cycle arrest in response to DNA damage. This protein forms a heterotrimeric complex with checkpoint proteins RAD9 and RAD1. In response to DNA damage, the trimeric complex interacts with another protein complex consisting of checkpoint protein RAD17 and four small subunits of the replication factor C (RFC), which loads the combined complex onto the chromatin. The DNA damage induced chromatin binding has been shown to depend on the activation of the checkpoint kinase ATM, and is thought to be an early checkpoint signaling event. Alternative splicing results in multiple transcript variants.

    分子量

    32 kDa

    基因ID

    3364

    UniProt

    O60921
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