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HINT1 抗体

This 兔 多克隆 anti-HINT1 antibody specifically detects HINT1 in WB, ELISA, IHC 和 IP. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7115028
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for HINT1 抗体 (ABIN7115028)

抗原

See all HINT1 抗体
HINT1 (Histidine Triad Nucleotide Binding Protein 1 (HINT1))

适用

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人, 小鼠, 大鼠

宿主

  • 60
  • 4

克隆类型

  • 49
  • 15
多克隆

标记

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This HINT1 antibody is un-conjugated

应用范围

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  • 3
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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
  • 原理

    HINT1 antibody

    纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    histidine triad nucleotide binding protein 1

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    HINT1 (Histidine Triad Nucleotide Binding Protein 1 (HINT1))

    别名

    HINT1

    背景

    Synonyms: Adenosine 5'-monophosphoramidase HINT1|Desumoylating isopeptidase HINT1|Histidine triad nucleotide-binding protein 1|Protein kinase C inhibitor 1|Protein kinase C-interacting protein 1 (PKCI-1)|HINT1|HINT|PKCI1|PRKCNH1

    Background: Hydrolyzes purine nucleotide phosphoramidates with a single phosphate group, including adenosine 5'monophosphoramidate(AMP-NH2), adenosine 5'monophosphomorpholidate(AMP-morpholidate) and guanosine 5'monophosphomorpholidate(GMP-morpholidate). Hydrolyzes lysyl-AMP(AMP-N-epsilon-(N-alpha-acetyl lysine methyl ester)) generated by lysine tRNA ligase, as well as Met-AMP, His-AMP and Asp-AMP, lysyl-GMP(GMP-N-epsilon-(N-alpha-acetyl lysine methyl ester)) and AMP-N-alanine methyl ester. Can also convert adenosine 5'-O-phosphorothioate and guanosine 5'-O-phosphorothioate to the corresponding nucleoside 5'-O-phosphates with concomitant release of hydrogen sulfide. In addition, functions as scaffolding protein that modulates transcriptional activation by the LEF1/TCF1-CTNNB1 complex and by the complex formed with MITF and CTNNB1. Modulates p53/TP53 levels and p53/TP53-mediated apoptosis. Modulates proteasomal degradation of target proteins by the SCF(SKP2-CUL1-F-box protein) E3 ubiquitin-protein ligase complex.

    分子量

    14 kDa

    基因ID

    3094

    UniProt

    P49773
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