HNRNPK 抗体
Quick Overview for HNRNPK 抗体 (ABIN7114983)
抗原
See all HNRNPK 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- HNRNPK antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- heterogeneous nuclear ribonucleoprotein K
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亚型
- IgG
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anti-Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) (AA 1-280) antibody
HNRNPK 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) antibodyHNRNPK 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) antibodyHNRNPK 适用: 人 WB, IHC, ELISA, IF, IP 宿主: 兔 Monoclonal 3G7 unconjugated Recombinant Antibody
anti-Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) antibodyHNRNPK 适用: 人, 小鼠, 大鼠, Cow, 非洲爪蟾, Hamster WB, IHC, ELISA, IF, IP, ICC, FACS, ChIP 宿主: 小鼠 Monoclonal 3C2 unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) (AA 1-463) antibodyHNRNPK 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) (pSer284) antibodyHNRNPK 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) (AA 371-420) antibodyHNRNPK 适用: 人, 小鼠, 大鼠, Cow, 兔, 犬, 斑马鱼, 小鸡, 豚鼠, 山羊, 马, 猴, 非洲爪蟾, Pig, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) (N-Term) antibodyHNRNPK 适用: 人, 小鼠, 大鼠, Cow, 兔, 犬, 小鸡, 豚鼠, 山羊, 马, 猴, 非洲爪蟾, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) (C-Term) antibodyHNRNPK 适用: 人, 小鼠, 大鼠, 犬, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) (N-Term) antibodyHNRNPK 适用: 人, 小鼠, 大鼠, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:2000, IHC: 1:50-1:200, IF: 1:10-1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- HNRNPK (Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK))
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别名
- HNRNPK
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背景
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Synonyms: Heterogeneous nuclear ribonucleoprotein K (hnRNP K)|Transformation up-regulated nuclear protein (TUNP)|HNRNPK|HNRPK
Background: One of the major pre-mRNA-binding proteins. Binds tenaciously to poly(C) sequences. Likely to play a role in the nuclear metabolism of hnRNAs, particularly for pre-mRNAs that contain cytidine-rich sequences. Can also bind poly(C) single-stranded DNA. Plays an important role in p53/TP53 response to DNA damage, acting at the level of both transcription activation and repression. When sumoylated, acts as a transcriptional coactivator of p53/TP53, playing a role in p21/CDKN1A and 14-3-3 sigma/SFN induction(By similarity). As far as transcription repression is concerned, acts by interacting with long intergenic RNA p21(lincRNA-p21), a non-coding RNA induced by p53/TP53. This interaction is necessary for the induction of apoptosis, but not cell cycle arrest.
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分子量
- 51 kDa
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基因ID
- 3190
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UniProt
- P61978
抗原
-
