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HNRNPK 抗体

This anti-HNRNPK antibody is a 兔 多克隆 antibody detecting HNRNPK in WB, IHC, ELISA, IF, IP 和 FACS. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7114983
发货至: 中国

Quick Overview for HNRNPK 抗体 (ABIN7114983)

抗原

See all HNRNPK 抗体
HNRNPK (Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This HNRNPK antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), Flow Cytometry (FACS)
  • 纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    heterogeneous nuclear ribonucleoprotein K

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:2000, IP: 1:500-1:2000, IHC: 1:50-1:200, IF: 1:10-1:100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    HNRNPK (Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK))

    别名

    HNRNPK

    背景

    Synonyms:CSBP, hnRNP K, HNRNPK, HNRPK, TUNP Background:One of the major pre-mRNA-binding proteins. Binds tenaciously to poly(C) sequences. Likely to play a role in the nuclear metabolism of hnRNAs, particularly for pre-mRNAs that contain cytidine-rich sequences. Can also bind poly(C) single-stranded DNA. Plays an important role in p53/TP53 response to DNA damage, acting at the level of both transcription activation and repression. When sumoylated, acts as a transcriptional coactivator of p53/TP53, playing a role in p21/CDKN1A and 14-3-3 sigma/SFN induction(By similarity). As far as transcription repression is concerned, acts by interacting with long intergenic RNA p21(lincRNA-p21), a non-coding RNA induced by p53/TP53. This interaction is necessary for the induction of apoptosis, but not cell cycle arrest.

    分子量

    51 kDa

    基因ID

    3190

    UniProt

    P61978
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