GRP78 抗体
Quick Overview for GRP78 抗体 (ABIN7114888)
抗原
See all GRP78 (HSPA5) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- HSPA5 antibody
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纯化方法
- Protein A+G purification
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- Endoplasmic reticulum chaperone BiP
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亚型
- IgG1
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应用备注
- WB: 1:2000-1:20000, IHC: 1:50-1:200, IF: 1:50-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- GRP78 (HSPA5) (Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5))
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别名
- HSPA5
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背景
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Synonyms: Endoplasmic reticulum chaperone BiP|78 kDa glucose-regulated protein (GRP-78)|Binding-immunoglobulin protein (BiP)|Heat shock protein 70 family protein 5 (HSP70 family protein 5)|Heat shock protein family A member 5|Immunoglobulin heavy chain-binding protein|HSPA5|GRP78
Background: GRP78 (HSPA5), also referred to as 'immunoglobulin heavy chain-binding protein' (BiP), is a member of the heat-shock protein-70 (HSP70) family and is involved in the folding and assembly of proteins in the endoplasmic reticulum (ER).It is a constitutively expressed resident protein of the ER in all eukaryotic cells. Recently it has been reported that GRP78 is associated with apoptosis or inhibition of cancer cell growth.
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分子量
- 70-78 kDa
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UniProt
- P11021
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途径
- Thyroid Hormone Synthesis, ER-Nucleus Signaling
抗原
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