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Histone H3.3 抗体

This anti-Histone H3.3 antibody is a 兔 多克隆 antibody detecting Histone H3.3 in ELISA 和 WB. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7114851
发货至: 中国

Quick Overview for Histone H3.3 抗体 (ABIN7114851)

抗原

See all Histone H3.3 (H3F3A) 抗体
Histone H3.3 (H3F3A) (H3 Histone, Family 3A (H3F3A))

适用

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人, 小鼠, 大鼠

宿主

  • 60
  • 7

克隆类型

  • 49
  • 18
多克隆

标记

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This Histone H3.3 antibody is un-conjugated

应用范围

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ELISA, Western Blotting (WB)
  • 原理

    Histone H3.3 antibody

    纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    H3 histone, family 3B(H3.3B)

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    Histone H3.3 (H3F3A) (H3 Histone, Family 3A (H3F3A))

    别名

    Histone H3.3

    背景

    Synonyms: Histone H3.3|H3-3A|H3.3A|H3F3|H3F3A

    Background: Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

    分子量

    17 kDa

    基因ID

    3021

    UniProt

    P84243
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