GEMIN8 抗体
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北京 101111
Quick Overview for GEMIN8 抗体 (ABIN7114530)
抗原
See all GEMIN8 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- GEMIN8 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- gem(nuclear organelle) associated protein 8
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亚型
- IgG
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anti-Gem (Nuclear Organelle) Associated Protein 8 (GEMIN8) (AA 1-242) antibody
GEMIN8 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Gem (Nuclear Organelle) Associated Protein 8 (GEMIN8) antibodyKD Validated GEMIN8 适用: 人 WB 宿主: 小鼠 Monoclonal 24GB13110 unconjugated
anti-Gem (Nuclear Organelle) Associated Protein 8 (GEMIN8) (C-Term) antibodyGEMIN8 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Gem (Nuclear Organelle) Associated Protein 8 (GEMIN8) antibodyGEMIN8 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- GEMIN8 (Gem (Nuclear Organelle) Associated Protein 8 (GEMIN8))
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别名
- GEMIN8
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背景
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Synonyms: Gem-associated protein 8 (Gemin-8)|Protein FAM51A1|GEMIN8|FAM51A1
Background: The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins(snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus.
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分子量
- 32 kDa
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基因ID
- 54960
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UniProt
- Q9NWZ8
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途径
- Ribonucleoprotein Complex Subunit Organization
抗原
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