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GEMIN8 抗体 (AA 1-242) (FITC)

GEMIN8 适用: 人 宿主: 兔 Polyclonal FITC
产品编号 ABIN7153771
发货至: 中国
  • 抗原 See all GEMIN8 抗体
    GEMIN8 (Gem (Nuclear Organelle) Associated Protein 8 (GEMIN8))
    抗原表位
    • 8
    • 7
    • 5
    • 5
    AA 1-242
    适用
    • 31
    • 9
    • 8
    宿主
    • 29
    • 2
    克隆类型
    • 29
    • 2
    多克隆
    标记
    • 11
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GEMIN8 antibody is conjugated to FITC
    应用范围
    请咨询
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Gem-associated protein 8 protein (1-242AA)
    亚型
    IgG
    Top Product
    Discover our top product GEMIN8 Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    GEMIN8 (Gem (Nuclear Organelle) Associated Protein 8 (GEMIN8))
    别名
    GEMIN8 (GEMIN8 产品)
    别名
    FAM51A1 antibody, B130034M20Rik antibody, B930082C09Rik antibody, BC023488 antibody, gemin-8 antibody, gem nuclear organelle associated protein 8 antibody, gemin8 antibody, GEMIN8 antibody, Gemin8 antibody
    背景

    Background: The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus.

    Aliases: GEMIN8 antibody, FAM51A1Gem-associated protein 8 antibody, Gemin-8 antibody, Protein FAM51A1 antibody

    UniProt
    Q9NWZ8
    途径
    Ribonucleoprotein Complex Subunit Organization
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