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FBP1 抗体

This anti-FBP1 antibody is a 兔 多克隆 antibody detecting FBP1 in WB, ELISA, IHC, IF 和 IP. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7114350
发货至: 中国

Quick Overview for FBP1 抗体 (ABIN7114350)

抗原

See all FBP1 抗体
FBP1 (Fructose-1,6-Bisphosphatase 1 (FBP1))

适用

  • 57
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  • 1
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  • 1
人, 小鼠, 大鼠

宿主

  • 56
  • 3
  • 2

克隆类型

  • 56
  • 5
多克隆

标记

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  • 1
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This FBP1 antibody is un-conjugated

应用范围

  • 49
  • 15
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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
  • 原理

    FBP1 antibody

    纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    fructose-1,6-bisphosphatase 1

    亚型

    IgG
  • 应用备注

    WB: 1:5000-1:20000, IP: 1:500-1:1000, IHC: 1:100-1:400, IF: 1:50-1:500

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    FBP1 (Fructose-1,6-Bisphosphatase 1 (FBP1))

    别名

    FBP1

    背景

    Synonyms: Fructose-1,6-bisphosphatase 1 (FBPase 1)|D-fructose-1,6-bisphosphate 1-phosphohydrolase 1|Liver FBPase|FBP1|FBP

    Background: Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations, acting as a rate-limiting enzyme in gluconeogenesis. Plays a role in regulating glucose sensing and insulin secretion of pancreatic beta-cells. Appears to modulate glycerol gluconeogenesis in liver. Important regulator of appetite and adiposity, increased expression of the protein in liver after nutrient excess increases circulating satiety hormones and reduces appetite-stimulating neuropeptides and thus seems to provide a feedback mechanism to limit weight gain.

    分子量

    37 kDa

    基因ID

    2203

    UniProt

    P09467

    途径

    Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Dicarboxylic Acid Transport
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