FBP1 抗体
Quick Overview for FBP1 抗体 (ABIN7114350)
抗原
See all FBP1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- FBP1 antibody
-
纯化方法
- Immunogen affinity purified
-
纯度
- ≥95 % as determined by SDS-PAGE
-
免疫原
- fructose-1,6-bisphosphatase 1
-
亚型
- IgG
-
-
-
-
应用备注
- WB: 1:5000-1:20000, IP: 1:500-1:1000, IHC: 1:100-1:400, IF: 1:50-1:500
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze / thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- -20°C for 12 months
-
有效期
- 12 months
-
-
- FBP1 (Fructose-1,6-Bisphosphatase 1 (FBP1))
-
别名
- FBP1
-
背景
-
Synonyms: Fructose-1,6-bisphosphatase 1 (FBPase 1)|D-fructose-1,6-bisphosphate 1-phosphohydrolase 1|Liver FBPase|FBP1|FBP
Background: Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations, acting as a rate-limiting enzyme in gluconeogenesis. Plays a role in regulating glucose sensing and insulin secretion of pancreatic beta-cells. Appears to modulate glycerol gluconeogenesis in liver. Important regulator of appetite and adiposity, increased expression of the protein in liver after nutrient excess increases circulating satiety hormones and reduces appetite-stimulating neuropeptides and thus seems to provide a feedback mechanism to limit weight gain.
-
分子量
- 37 kDa
-
基因ID
- 2203
-
UniProt
- P09467
-
途径
- Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Dicarboxylic Acid Transport
抗原
-