FOXA2 抗体
Quick Overview for FOXA2 抗体 (ABIN7114288)
抗原
See all FOXA2 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- FOXA2 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- forkhead box A2
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亚型
- IgG
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anti-Forkhead Box A2 (FOXA2) (AA 363-457) antibody
FOXA2 适用: 人 WB, ELISA, IF, IP, RNAi 宿主: 小鼠 Monoclonal 7E6 unconjugated
anti-Forkhead Box A2 (FOXA2) (Middle Region) antibodyFOXA2 适用: 人, 小鼠, 大鼠, 犬, 兔, 马, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box A2 (FOXA2) (C-Term) antibodyVerified FOXA2 适用: 人, 大鼠 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Forkhead Box A2 (FOXA2) (AA 201-300) antibodyFOXA2 适用: 人, 小鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box A2 (FOXA2) (AA 363-457) antibodyFOXA2 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2F12 unconjugated
anti-Forkhead Box A2 (FOXA2) (AA 363-457) antibodyFOXA2 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 4G11 unconjugated
anti-Forkhead Box A2 (FOXA2) (AA 380-407) antibodyFOXA2 适用: 人, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box A2 (FOXA2) (AA 128-157) antibodyFOXA2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box A2 (FOXA2) antibodyFOXA2 适用: 人 WB, IF, IP 宿主: 兔 Monoclonal unconjugated
anti-Forkhead Box A2 (FOXA2) antibodyFOXA2 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 7H4B7 unconjugated
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应用备注
- WB: 1:500-1:5000, IP: 1:200-1:1000, IHC: 1:20-1:200, IF: 1:50-1:500
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- FOXA2 (Forkhead Box A2 (FOXA2))
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别名
- FOXA2
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背景
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Synonyms: Hepatocyte nuclear factor 3-beta (HNF-3-beta, HNF-3B)|Forkhead box protein A2|Transcription factor 3B (TCF-3B)|FOXA2|HNF3B|TCF3B
Background: Transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues. Is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. Binds DNA with the consensus sequence 5'-[AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3'(By similarity). In embryonic development is required for notochord formation. Involved in the development of multiple endoderm-derived organ systems such as the liver, pancreas and lungs, FOXA1 and FOXA2 seem to have at least in part redundant roles. Originally described as a transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes. Involved in glucose homeostasis, regulates the expression of genes important for glucose sensing in pancreatic beta-cells and glucose homeostasis. Involved in regulation of fat metabolism. Binds to fibrinogen beta promoter and is involved in IL6-induced fibrinogen beta transcriptional activation.
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分子量
- 60 kDa
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基因ID
- 3170
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UniProt
- Q9Y261
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途径
- Dopaminergic Neurogenesis, Regulation of Carbohydrate Metabolic Process
抗原
-
