FRS2 抗体
Quick Overview for FRS2 抗体 (ABIN7114220)
抗原
See all FRS2 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- FRS2 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- fibroblast growth factor receptor substrate 2
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亚型
- IgG
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应用备注
- WB: 1:500-1:5000, IHC: 1:20-1:200, IF: 1:10-1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- FRS2 (Fibroblast Growth Factor Receptor Substrate 2 (FRS2))
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别名
- FRS2
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背景
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Synonyms: Fibroblast growth factor receptor substrate 2 (FGFR substrate 2)|FGFR-signaling adaptor SNT|Suc1-associated neurotrophic factor target 1 (SNT-1)|FRS2
Background: Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.
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分子量
- 60 kDa
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基因ID
- 10818
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UniProt
- Q8WU20
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途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Signaling Events mediated by VEGFR1 and VEGFR2
抗原
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