FDPS 抗体
Quick Overview for FDPS 抗体 (ABIN7114125)
抗原
See all FDPS 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- FDPS antibody
-
纯化方法
- Immunogen affinity purified
-
纯度
- ≥95 % as determined by SDS-PAGE
-
免疫原
- farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase)
-
亚型
- IgG
-
-
-
-
应用备注
- WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:100
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze / thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- -20°C for 12 months
-
有效期
- 12 months
-
-
- FDPS (Farnesyl Diphosphate Synthase (FDPS))
-
别名
- FDPS
-
背景
-
Synonyms: Farnesyl pyrophosphate synthase (FPP synthase, FPS)|(2E,6E)-farnesyl diphosphate synthase|Dimethylallyltranstransferase|Farnesyl diphosphate synthase|Geranyltranstransferase|FDPS|FPS|KIAA1293
Background: This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene.
-
分子量
- 38 kDa
-
基因ID
- 2224
-
UniProt
- P14324
-
途径
- Regulation of Muscle Cell Differentiation
抗原
-