EIF5A 抗体
Quick Overview for EIF5A 抗体 (ABIN7113978)
抗原
See all EIF5A 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- EIF5A antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- eukaryotic translation initiation factor 5A
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亚型
- IgG
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应用备注
- WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- EIF5A (Eukaryotic Translation Initiation Factor 5A (EIF5A))
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别名
- EIF5A
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背景
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Synonyms: Eukaryotic translation initiation factor 5A-1 (eIF-5A-1, eIF-5A1)|Eukaryotic initiation factor 5A isoform 1 (eIF-5A)|Rev-binding factor|eIF-4D|EIF5A
Background: mRNA-binding protein involved in translation elongation. Has an important function at the level of Mrna turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. With syntenin SDCBP, functions as a regulator of p53/TP53 and p53/TP53-dependent apoptosis. Regulates also TNF-alpha-mediated apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation. Also described as a cellular cofactor of human T-cell leukemia virus type I (HTLV-1) Rex protein and of human immunodeficiency virus type 1 (HIV-1) Rev protein, essential for mRNA export of retroviral transcripts.
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分子量
- 17 kDa
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基因ID
- 1984
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UniProt
- P63241
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途径
- Regulation of Muscle Cell Differentiation
抗原
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