EIF3D 抗体
Quick Overview for EIF3D 抗体 (ABIN7113953)
抗原
See all EIF3D 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- EIF3D antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- eukaryotic translation initiation factor 3, subunit D
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- EIF3D (Eukaryotic Translation Initiation Factor 3, Subunit D (EIF3D))
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别名
- EIF3D
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背景
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Synonyms: Eukaryotic translation initiation factor 3 subunit D (eIF3d)|Eukaryotic translation initiation factor 3 subunit 7|eIF-3-zeta|eIF3 p66|EIF3D|EIF3S7
Background: Component of the eukaryotic translation initiation factor 3(eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex(43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. In case of FCV infection, plays a role in the ribosomal termination-reinitiation event leading to the translation of VP2(PubMed:18056426).
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分子量
- 66 kDa
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基因ID
- 8664
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UniProt
- O15371
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途径
- Ribonucleoprotein Complex Subunit Organization
抗原
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