EIF3S1 抗体
Quick Overview for EIF3S1 抗体 (ABIN7113950)
抗原
See all EIF3S1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- EIF3J antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- eukaryotic translation initiation factor 3, subunit J
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200, IF: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- EIF3S1 (Eukaryotic Translation Initiation Factor 3 Subunit J (EIF3S1))
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别名
- EIF3J
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背景
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Synonyms: Eukaryotic translation initiation factor 3 subunit J (eIF3j)|Eukaryotic translation initiation factor 3 subunit 1|eIF-3-alpha|eIF3 p35|EIF3J|EIF3S1
Background: Component of the eukaryotic translation initiation factor 3(eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex(43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. This subunit binds directly within the mRNA entry channel of the 40S ribosome to the aminoacyl(A) site. It may regulate the interaction between the 43S PIC and mRNA.
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分子量
- 35 kDa
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基因ID
- 8669
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UniProt
- O75822
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途径
- Ribonucleoprotein Complex Subunit Organization
抗原
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