EIF3S1 抗体 (Internal Region)
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- 抗原 See all EIF3S1 抗体
- EIF3S1 (Eukaryotic Translation Initiation Factor 3 Subunit J (EIF3S1))
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抗原表位
- Internal Region
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This EIF3S1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- EIF3J Antibody detects endogenous levels of total EIF3J.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human EIF3J, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product EIF3S1 Primary Antibody
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anti-Eukaryotic Translation Initiation Factor 3 Subunit J (EIF3S1) antibody
EIF3S1 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3 Subunit J (EIF3S1) (AA 1-258) antibodyEIF3S1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3 Subunit J (EIF3S1) (AA 1-258) antibodyEIF3S1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3 Subunit J (EIF3S1) (AA 5-115) antibodyEIF3S1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3 Subunit J (EIF3S1) (AA 157-258) antibodyEIF3S1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3 Subunit J (EIF3S1) (AA 230-280) antibodyEIF3S1 适用: 人, 小鼠, 犬, 马 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:1000-3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- EIF3S1 (Eukaryotic Translation Initiation Factor 3 Subunit J (EIF3S1))
- 别名
- EIF3J (EIF3S1 产品)
- 别名
- GB12381 antibody, An18g06260 antibody, AO090003000054 antibody, EIF3S1 antibody, eIF3j antibody, eIF3-alpha antibody, eIF3-p35 antibody, Eif3s1 antibody, eif3s1 antibody, 1810016I04Rik antibody, 2700079K05Rik antibody, AA409117 antibody, AA409446 antibody, C78575 antibody, Eif3j antibody, Eif3j-1 antibody, Eif3j-2 antibody, Eif3j2 antibody, eIF-3-alpha-A antibody, eIF-3-alpha-B antibody, eIF3j-A antibody, eIF3j-B antibody, eukaryotic translation initiation factor 3 subunit J antibody, eukaryotic translation initiation factor 3, subunit J antibody, Eukaryotic translation initiation factor 3 subunit J antibody, eukaryotic translation initiation factor 3 subunit 1 antibody, eukaryotic translation initiation factor 3 subunit J S homeolog antibody, eukaryotic translation initiation factor 3, subunit J1 antibody, LOC409796 antibody, ANI_1_830164 antibody, AOR_1_94154 antibody, Eif3j antibody, EIF3J antibody, eif3j antibody, LOC733089 antibody, eif3j.S antibody, Eif3j1 antibody
- 背景
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Description: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis (PubMed:25849773, PubMed:27462815). The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression (PubMed:25849773).
Gene: EIF3J
- 分子量
- 29 kDa
- 基因ID
- 8669
- UniProt
- O75822
- 途径
- Ribonucleoprotein Complex Subunit Organization
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