ESR2 抗体
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- 抗原 See all ESR2 抗体
- ESR2 (Estrogen Receptor 2 (ESR2))
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适用
- 人, 小鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This ESR2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 纯化方法
- Protein A+G purification
- 纯度
- ≥95 % as determined by SDS-PAGE
- 免疫原
- estrogen receptor 2(ER beta)
- 克隆位点
- 0A10
- 亚型
- IgG1
- Top Product
- Discover our top product ESR2 Primary Antibody
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- 应用备注
- WB: 1:500-1:2000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- 有效期
- 12 months
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- 抗原
- ESR2 (Estrogen Receptor 2 (ESR2))
- 别名
- ESR2 (ESR2 产品)
- 背景
- Synonyms:ER BETA, Erb, ESR BETA, ESR2, ESRB, ESTRB, estrogen receptor 2 (ER beta), Estrogen receptor beta, NR3A2 Background:Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1, and activates expression of reporter genes containing estrogen response elements(ERE) in an estrogen-dependent manner(PubMed:20074560). Isoform beta-cx lacks ligand binding ability and has no or only very low ere binding activity resulting in the loss of ligand-dependent transactivation ability. DNA-binding by ESR1 and ESR2 is rapidly lost at 37 degrees Celsius in the absence of ligand while in the presence of 17 beta-estradiol and 4-hydroxy-tamoxifen loss in DNA-binding at elevated temperature is more gradual.
- 分子量
- 50 kDa
- 基因ID
- 2100
- UniProt
- Q92731
- 途径
- Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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