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ESR2 抗体 (AA 1-300)

This anti-ESR2 antibody is a 小鼠 单克隆 antibody detecting ESR2 in WB 和 ELISA. Suitable for 人 和 小鼠.
产品编号 ABIN7113900
发货至: 中国

Quick Overview for ESR2 抗体 (AA 1-300) (ABIN7113900)

抗原

See all ESR2 抗体
ESR2 (Estrogen Receptor 2 (ESR2))

适用

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人, 小鼠

宿主

  • 157
  • 38
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  • 1
小鼠

克隆类型

  • 153
  • 46
单克隆

标记

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This ESR2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA

克隆位点

0A10
  • 抗原表位

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    AA 1-300

    原理

    ESR2 antibody

    纯化方法

    Protein A+G purification

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    Immunogen sequence: 1-300aa

    Immunogen: estrogen receptor 2(ER beta)

    亚型

    IgG1
  • 应用备注

    WB: 1:500-1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    ESR2 (Estrogen Receptor 2 (ESR2))

    别名

    ESR2

    背景

    Synonyms: Estrogen receptor beta (ER-beta)|Nuclear receptor subfamily 3 group A member 2|ESR2|ESTRB|NR3A2

    Background: Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1, and activates expression of reporter genes containing estrogen response elements(ERE) in an estrogen-dependent manner(PubMed:20074560). Isoform beta-cx lacks ligand binding ability and has no or only very low ere binding activity resulting in the loss of ligand-dependent transactivation ability. DNA-binding by ESR1 and ESR2 is rapidly lost at 37 degrees Celsius in the absence of ligand while in the presence of 17 beta-estradiol and 4-hydroxy-tamoxifen loss in DNA-binding at elevated temperature is more gradual.

    分子量

    50 kDa

    基因ID

    2100

    UniProt

    Q92731

    途径

    Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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