ESR2 抗体 (AA 1-300)
Quick Overview for ESR2 抗体 (AA 1-300) (ABIN7113900)
抗原
See all ESR2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 1-300
-
原理
- ESR2 antibody
-
纯化方法
- Protein A+G purification
-
纯度
- ≥95 % as determined by SDS-PAGE
-
免疫原
-
Immunogen sequence: 1-300aa
Immunogen: estrogen receptor 2(ER beta)
-
亚型
- IgG1
-
-
-
-
应用备注
- WB: 1:500-1:2000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze / thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- -20°C for 12 months
-
有效期
- 12 months
-
-
- ESR2 (Estrogen Receptor 2 (ESR2))
-
别名
- ESR2
-
背景
-
Synonyms: Estrogen receptor beta (ER-beta)|Nuclear receptor subfamily 3 group A member 2|ESR2|ESTRB|NR3A2
Background: Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1, and activates expression of reporter genes containing estrogen response elements(ERE) in an estrogen-dependent manner(PubMed:20074560). Isoform beta-cx lacks ligand binding ability and has no or only very low ere binding activity resulting in the loss of ligand-dependent transactivation ability. DNA-binding by ESR1 and ESR2 is rapidly lost at 37 degrees Celsius in the absence of ligand while in the presence of 17 beta-estradiol and 4-hydroxy-tamoxifen loss in DNA-binding at elevated temperature is more gradual.
-
分子量
- 50 kDa
-
基因ID
- 2100
-
UniProt
- Q92731
-
途径
- Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
抗原
-