Ensa 抗体
Quick Overview for Ensa 抗体 (ABIN7113813)
抗原
See all Ensa (ENSA) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- ENSA antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- endosulfine alpha
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000, IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- Ensa (ENSA) (Endosulfine alpha (ENSA))
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别名
- ENSA
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背景
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Synonyms: Alpha-endosulfine|ARPP-19e|ENSA
Background: Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A(PP2A) during mitosis. When phosphorylated at Ser-67 during mitosis, specifically interacts with PPP2R2D(PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase(By similarity). Also acts as a stimulator of insulin secretion by interacting with sulfonylurea receptor(ABCC8), thereby preventing sulfonylurea from binding to its receptor and reducing K(ATP) channel currents.
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分子量
- 19 kDa
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基因ID
- 2029
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UniProt
- O43768
抗原
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