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DKK1 抗体

The 兔 多克隆 anti-DKK1 antibody (ABIN7113474) specifically detects DKK1 in WB, ELISA, IHC 和 IF. The antibody is reactive with 人, 大鼠 和 小鼠 samples.
产品编号 ABIN7113474
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for DKK1 抗体 (ABIN7113474)

抗原

See all DKK1 抗体
DKK1 (Dickkopf Homolog 1 (DKK1))

适用

  • 126
  • 43
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  • 4
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  • 3
  • 3
  • 3
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  • 3
  • 2
  • 1
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人, 大鼠, 小鼠

宿主

  • 116
  • 15
  • 4
  • 1
  • 1
  • 1

克隆类型

  • 99
  • 39
多克隆

标记

  • 75
  • 12
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  • 4
  • 4
  • 1
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This DKK1 antibody is un-conjugated

应用范围

  • 87
  • 52
  • 33
  • 17
  • 13
  • 13
  • 13
  • 13
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  • 10
  • 3
  • 3
  • 1
  • 1
  • 1
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  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 原理

    DKK1 antibody

    纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    dickkopf homolog 1

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:1000, IHC: 1:50-1:500, IF: 1:10-1:100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    DKK1 (Dickkopf Homolog 1 (DKK1))

    别名

    DKK1

    背景

    Synonyms: Dickkopf-related protein 1 (Dickkopf-1, Dkk-1, hDkk-1)|SK|DKK1

    Background: Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.

    分子量

    30-35 kDa

    基因ID

    22943

    UniProt

    O94907

    途径

    WNT signaling, Regulation of Muscle Cell Differentiation, Positive Regulation of fat Cell Differentiation
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