DDX21 抗体
Quick Overview for DDX21 抗体 (ABIN7113335)
抗原
See all DDX21 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- DDX21 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- DEAD(Asp-Glu-Ala-Asp) box polypeptide 21
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亚型
- IgG
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anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 21 (DDX21) antibody
DDX21 适用: 人, 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 21 (DDX21) (N-Term) antibodyDDX21 适用: 人, 大鼠, 马, Saccharomyces cerevisiae WB 宿主: 兔 Polyclonal unconjugated
anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 21 (DDX21) (C-Term) antibodyDDX21 适用: 人, Cow, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 21 (DDX21) (N-Term) antibodyDDX21 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 21 (DDX21) (C-Term) antibodyDDX21 适用: 人, 大鼠, 马, 犬, Pig, Cow, 豚鼠, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 21 (DDX21) (AA 128-156), (N-Term) antibodyDDX21 适用: 人 WB 宿主: 兔 Polyclonal RB37016 unconjugated
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应用备注
- WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200, IF: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- DDX21 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 21 (DDX21))
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别名
- DDX21
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背景
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Synonyms: Nucleolar RNA helicase 2|DEAD box protein 21|Gu-alpha|Nucleolar RNA helicase Gu|Nucleolar RNA helicase II|RH II/Gu|DDX21
Background: RNA helicase that acts as a sensor of the transcriptional status of both RNA polymerase(Pol) I and II: promotes ribosomal RNA(rRNA) processing and transcription from polymerase II(Pol II)(PubMed:25470060). Binds various RNAs, such as rRNAs, snoRNAs, 7SK and, at lower extent, mRNAs(PubMed:25470060). In the nucleolus, localizes to rDNA locus, where it directly binds rRNAs and snoRNAs, and promotes rRNA transcription, processing and modification. Required for rRNA 2'-O-methylation, possibly by promoting the recruitment of late-acting snoRNAs SNORD56 and SNORD58 with pre-ribosomal complexes(PubMed:25470060, PubMed:25477391). In the nucleoplasm, binds 7SK RNA and is recruited to the promoters of Pol II-transcribed genes: acts by facilitating the release of P-TEFb from inhibitory 7SK snRNP in a manner that is dependent on its helicase activity, thereby promoting transcription of its target genes(PubMed:25470060). Functions as cofactor for JUN-activated transcription: required for phosphorylation of JUN at 'Ser-77'(PubMed:11823437, PubMed:25260534). Can unwind double-stranded RNA(helicase) and can fold or introduce a secondary structure to a single-stranded RNA(foldase)(PubMed:9461305). Involved in rRNA processing(PubMed:14559904, PubMed:18180292).
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分子量
- 87 kDa
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基因ID
- 9188
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UniProt
- Q9NR30
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途径
- SARS-CoV-2 Protein Interactome
抗原
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