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DDX21 抗体 (N-Term)

DDX21 适用: 人, 大鼠, 马, Saccharomyces cerevisiae WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2775197
发货至: 中国
  • 抗原 See all DDX21 抗体
    DDX21 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 21 (DDX21))
    抗原表位
    • 8
    • 8
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 38
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    人, 大鼠, 马, Saccharomyces cerevisiae
    宿主
    • 38
    克隆类型
    • 37
    • 1
    多克隆
    标记
    • 21
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DDX21 antibody is un-conjugated
    应用范围
    • 27
    • 14
    • 7
    • 7
    • 6
    • 2
    • 1
    • 1
    Western Blotting (WB)
    序列
    MPGKLRSDAG LESDTAMKKG ETLRKQTEEK EKKEKPKSDK TEEIAEEEET
    预测反应
    Horse: 79%, Human: 100%, Rat: 91%, Yeast: 83%
    产品特性
    This is a rabbit polyclonal antibody against DDX21. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human DDX21
    Top Product
    Discover our top product DDX21 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 783 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • De Wever, Lloyd, Nasa, Nimick, Trinkle-Mulcahy, Gourlay, Morrice, Moorhead: "Isolation of human mitotic protein phosphatase complexes: identification of a complex between protein phosphatase 1 and the RNA helicase Ddx21." in: PLoS ONE, Vol. 7, Issue 6, pp. e39510, (2012) (PubMed).

    Naji, Ambrus, Cimerman?i?, Reyes, Johnson, Filbrandt, Huber, Vesely, Krogan, Yates, Saphire, Gerace: "Host cell interactome of HIV-1 Rev includes RNA helicases involved in multiple facets of virus production." in: Molecular & cellular proteomics : MCP, Vol. 11, Issue 4, pp. M111.015313, (2012) (PubMed).

  • 抗原
    DDX21 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 21 (DDX21))
    别名
    DDX21 (DDX21 产品)
    别名
    MGC130693 antibody, DDX21 antibody, cb960 antibody, wu:fi30c07 antibody, wu:fi34d08 antibody, GUA antibody, GURDB antibody, RH-II/GU antibody, RH-II/GuA antibody, Ddx21a antibody, AI255159 antibody, AL022742 antibody, D10Ertd645e antibody, D10Wsu42e antibody, DEAD-box helicase 21 L homeolog antibody, DExD-box helicase 21 antibody, DEAD-box helicase 21 antibody, DEAD (Asp-Glu-Ala-Asp) box helicase 21 antibody, DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 antibody, ddx21.L antibody, DDX21 antibody, ddx21 antibody, Ddx21 antibody
    背景
    DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an antigen recognized by autoimmune antibodies from a patient with watermelon stomach disease. This protein unwinds double-stranded RNA, folds single-stranded RNA, and may play important roles in ribosomal RNA biogenesis, RNA editing, RNA transport, and general transcription.
    Alias Symbols: GUA, GURDB, RH-II/GU, RH-II/GuA
    Protein Interaction Partner: HUWE1, PA2G4, KPNA3, CEP250, SUMO2, SUMO3, STAU1, IVNS1ABP, UBC, MDM2, LGR4, SUMO1, ERG, WWOX, EED, rev, SRPK2, SRPK3, FBXO6, TARDBP, LYN, AICDA, PAN2, vif, WHSC1, VCAM1, ITGA4, IL7R, FN1, CSNK2A1, YWHAE, SMURF1, H2AFX, APTX, ESR1, FTSJ3, PCDHA2, RRP7A, R
    Protein Size: 783
    分子量
    86 kDa
    基因ID
    9188
    NCBI登录号
    NM_004728, NP_004719
    UniProt
    Q9NR30
    途径
    SARS-CoV-2 Protein Interactome
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