CPEB1 抗体
Quick Overview for CPEB1 抗体 (ABIN7113294)
抗原
See all CPEB1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- CPEB1 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- cytoplasmic polyadenylation element binding protein 1
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000, IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- CPEB1 (Cytoplasmic Polyadenylation Element Binding Protein 1 (CPEB1))
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别名
- CPEB1
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背景
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Synonyms: Cytoplasmic polyadenylation element-binding protein 1 (CPE-BP1, CPE-binding protein 1, h-CPEB, hCPEB-1)|CPEB1|CPEB
Background: Sequence-specific RNA-binding protein that regulates mRNA cytoplasmic polyadenylation and translation initiation during oocyte maturation, early development and at postsynapse sites of neurons. Binds to the cytoplasmic polyadenylation element(CPE), an uridine-rich sequence element(consensus sequence 5'-UUUUUAU-3') within the mRNA 3'-UTR. In absence of phosphorylation and in association with TACC3 is also involved as a repressor of translation of CPE-containing mRNA, a repression that is relieved by phosphorylation or degradation(By similarity). Involved in the transport of CPE-containing mRNA to dendrites, those mRNAs may be transported to dendrites in a translationally dormant form and translationally activated at synapses(By similarity). Its interaction with APLP1 promotes local CPE-containing mRNA polyadenylation and translation activation(By similarity). Induces the assembly of stress granules in the absence of stress.
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分子量
- 54 kDa
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基因ID
- 64506
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UniProt
- Q9BZB8
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途径
- Synaptic Membrane
抗原
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