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Exportin 2 抗体

This anti-Exportin 2 antibody is a 兔 多克隆 antibody detecting Exportin 2 in WB, ELISA 和 IHC. Suitable for 人 和 小鼠.
产品编号 ABIN7113096
发货至: 中国

Quick Overview for Exportin 2 抗体 (ABIN7113096)

抗原

See all Exportin 2 (CSE1L) 抗体
Exportin 2 (CSE1L) (CSE1 Chromosome Segregation 1-Like (CSE1L))

适用

  • 36
  • 16
  • 10
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  • 5
  • 5
  • 4
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  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 29
  • 7
  • 1

克隆类型

  • 26
  • 11
多克隆

标记

  • 34
  • 1
  • 1
  • 1
This Exportin 2 antibody is un-conjugated

应用范围

  • 33
  • 19
  • 16
  • 10
  • 10
  • 10
  • 9
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    CSE1 chromosome segregation 1-like(yeast)

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:2000, IHC: 1:20-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    Exportin 2 (CSE1L) (CSE1 Chromosome Segregation 1-Like (CSE1L))

    别名

    CSE1L

    背景

    Synonyms:CAS, XPO2 Background:Export receptor for importin-alpha. Mediates importin-alpha re-export from the nucleus to the cytoplasm after import substrates(cargos) have been released into the nucleoplasm. In the nucleus binds cooperatively to importin-alpha and to the GTPase Ran in its active GTP-bound form. Docking of this trimeric complex to the nuclear pore complex(NPC) is mediated through binding to nucleoporins. Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP(induced by RANBP1 and RANGAP1, respectively) cause release of the importin-alpha from the export receptor. CSE1L/XPO2 then return to the nuclear compartment and mediate another round of transport. The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP-and GDP-bound forms of Ran between the cytoplasm and nucleus.

    分子量

    100-110 kDa

    基因ID

    1434

    UniProt

    P55060

    途径

    Protein targeting to Nucleus
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