C4BPB 抗体 (AA 18-252)
Quick Overview for C4BPB 抗体 (AA 18-252) (ABIN7113013)
抗原
See all C4BPB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 18-252
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原理
- C4BPB antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
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Immunogen sequence: 18-252aa
Immunogen: complement component 4 binding protein, beta
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亚型
- IgG
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应用备注
- WB: 1:500 - 1:2000, IHC: 1:50 - 1:100, IF: 1:50 - 1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- C4BPB (Complement Component 4 Binding Protein, beta (C4BPB))
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别名
- C4BPB
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背景
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Synonyms: C4b-binding protein beta chain|C4BPB
Background: This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants.
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分子量
- 40-45 kDa
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基因ID
- 725
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UniProt
- P20851
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途径
- Complement System
抗原
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