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C4BPB 抗体 (AA 18-252)

This anti-C4BPB antibody is a 兔 多克隆 antibody detecting C4BPB in WB, IHC, ELISA 和 IF. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7113013
发货至: 中国

Quick Overview for C4BPB 抗体 (AA 18-252) (ABIN7113013)

抗原

See all C4BPB 抗体
C4BPB (Complement Component 4 Binding Protein, beta (C4BPB))

适用

  • 38
  • 2
  • 2
  • 2
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 30
  • 8

克隆类型

  • 31
  • 7
多克隆

标记

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  • 1
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  • 1
This C4BPB antibody is un-conjugated

应用范围

  • 34
  • 18
  • 14
  • 9
  • 6
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  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 7
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 18-252

    原理

    C4BPB antibody

    纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    Immunogen sequence: 18-252aa

    Immunogen: complement component 4 binding protein, beta

    亚型

    IgG
  • 应用备注

    WB: 1:500 - 1:2000, IHC: 1:50 - 1:100, IF: 1:50 - 1:100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    C4BPB (Complement Component 4 Binding Protein, beta (C4BPB))

    别名

    C4BPB

    背景

    Synonyms: C4b-binding protein beta chain|C4BPB

    Background: This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants.

    分子量

    40-45 kDa

    基因ID

    725

    UniProt

    P20851

    途径

    Complement System
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