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CC2D1A 抗体

CC2D1A 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7112928
发货至: 中国
  • 抗原 See all CC2D1A 抗体
    CC2D1A (Coiled-Coil and C2 Domain Containing 1A (CC2D1A))
    适用
    人, 小鼠, 大鼠
    宿主
    • 32
    • 2
    克隆类型
    • 33
    • 1
    多克隆
    标记
    • 17
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CC2D1A antibody is un-conjugated
    应用范围
    • 25
    • 14
    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    coiled-coil and C2 domain containing 1A
    亚型
    IgG
    Top Product
    Discover our top product CC2D1A Primary Antibody
  • 应用备注
    WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    CC2D1A (Coiled-Coil and C2 Domain Containing 1A (CC2D1A))
    别名
    CC2D1A (CC2D1A 产品)
    别名
    mrt3 antibody, freud-1 antibody, FREUD-1 antibody, Freud-1/Aki1 antibody, MRT3 antibody, BC016188 antibody, Freud-1 antibody, Tape antibody, RGD1306108 antibody, coiled-coil and C2 domain containing 1A antibody, CC2D1A antibody, cc2d1a antibody, Cc2d1a antibody
    背景
    Synonyms:AKI1 Background:Transcription factor that binds specifically to the DRE(dual repressor element) and represses HTR1A gene transcription in neuronal cells. The combination of calcium and ATP specifically inactivates the binding with FRE. May play a role in the altered regulation of HTR1A associated with anxiety and major depression. Mediates HDAC-independent repression of HTR1A promoter in neuronal cell. Performs essential function in controlling functional maturation of synapses(By similarity). Plays distinct roles depending on its localization. When cytoplasmic, acts as a scaffold protein in the PI3K/PDK1/AKT pathway. Repressor of HTR1A when nuclear. In the centrosome, regulates spindle pole localization of the cohesin subunit SCC1/RAD21, thereby mediating centriole cohesion during mitosis.
    分子量
    130 kDa, 104 kDa
    基因ID
    54862
    UniProt
    Q6P1N0
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