CC2D1A 抗体
Quick Overview for CC2D1A 抗体 (ABIN7112928)
抗原
See all CC2D1A 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- CC2D1A antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- coiled-coil and C2 domain containing 1A
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亚型
- IgG
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anti-Coiled-Coil and C2 Domain Containing 1A (CC2D1A) (AA 1-951) antibody
CC2D1A 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Coiled-Coil and C2 Domain Containing 1A (CC2D1A) (AA 1-951) antibodyCC2D1A 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Coiled-Coil and C2 Domain Containing 1A (CC2D1A) (AA 1-150) antibodyCC2D1A 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Coiled-Coil and C2 Domain Containing 1A (CC2D1A) antibodyCC2D1A 适用: 人, 小鼠, 大鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Coiled-Coil and C2 Domain Containing 1A (CC2D1A) antibodyCC2D1A 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
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应用备注
- WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- CC2D1A (Coiled-Coil and C2 Domain Containing 1A (CC2D1A))
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别名
- CC2D1A
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背景
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Synonyms: Coiled-coil and C2 domain-containing protein 1A|Akt kinase-interacting protein 1|Five prime repressor element under dual repression-binding protein 1 (FRE under dual repression-binding protein 1, Freud-1)|Putative NF-kappa-B-activating protein 023N|CC2D1A|AKI1
Background: Transcription factor that binds specifically to the DRE(dual repressor element) and represses HTR1A gene transcription in neuronal cells. The combination of calcium and ATP specifically inactivates the binding with FRE. May play a role in the altered regulation of HTR1A associated with anxiety and major depression. Mediates HDAC-independent repression of HTR1A promoter in neuronal cell. Performs essential function in controlling functional maturation of synapses(By similarity). Plays distinct roles depending on its localization. When cytoplasmic, acts as a scaffold protein in the PI3K/PDK1/AKT pathway. Repressor of HTR1A when nuclear. In the centrosome, regulates spindle pole localization of the cohesin subunit SCC1/RAD21, thereby mediating centriole cohesion during mitosis.
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分子量
- 130 kDa, 104 kDa
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基因ID
- 54862
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UniProt
- Q6P1N0
抗原
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