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CEP152 抗体

CEP152 适用: 人, 小鼠 ELISA, WB, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7112602
发货至: 中国
  • 抗原 See all CEP152 抗体
    CEP152 (Centrosomal Protein 152kDa (CEP152))
    适用
    人, 小鼠
    宿主
    • 16
    • 1
    克隆类型
    • 16
    • 1
    多克隆
    标记
    • 10
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CEP152 antibody is un-conjugated
    应用范围
    • 8
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunoprecipitation (IP)
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    centrosomal protein 152kDa
    亚型
    IgG
    Top Product
    Discover our top product CEP152 Primary Antibody
  • 应用备注
    WB: 1:500-1:2000, IP: 1:200-1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    CEP152 (Centrosomal Protein 152kDa (CEP152))
    别名
    CEP152 (CEP152 产品)
    别名
    AI851464 antibody, mKIAA0912 antibody, RGD1305348 antibody, MCPH4 antibody, MCPH9 antibody, SCKL5 antibody, centrosomal protein 152 antibody, CEP152 antibody, Cep152 antibody
    背景
    Synonyms:KIAA0912 Background:Necessary for centrosome duplication, the function seems also to involve CEP63, CDK5RAP2 and WDR62 through a stepwise assembled complex at the centrosome that recruits CDK2 required for centriole duplication(PubMed:26297806). Acts as a molecular scaffold facilitating the interaction of PLK4 and CENPJ, 2 Molecules involved in centriole formation(PubMed:21059844, PubMed:20852615). Proposed to snatch PLK4 away from PLK4:CEP92 complexes in early G1 daughter centriole and to reposition PLK4 at the outer boundary of a newly forming CEP152 ring structure(PubMed:24997597). Also plays a key role in deuterosome-mediated centriole amplification in multiciliated that can generate more than 100 centrioles(By similarity). Overexpression of CEP152 can drive amplification of centrioles(PubMed:20852615).
    分子量
    110 kDa
    基因ID
    22995
    UniProt
    O94986
    途径
    M Phase
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