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- 抗原 See all CEP152 抗体
- CEP152 (Centrosomal Protein 152kDa (CEP152))
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抗原表位
- C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CEP152 antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- CEP152 Antibody detects endogenous levels of total CEP152.
- 预测反应
- Pig,Bovine,Horse,Sheep,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human CEP152, corresponding to a region within C-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product CEP152 Primary Antibody
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anti-Centrosomal Protein 152kDa (CEP152) (Internal Region) antibody
CEP152 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Centrosomal Protein 152kDa (CEP152) (Internal Region) antibodyCEP152 适用: 人, 小鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Centrosomal Protein 152kDa (CEP152) (AA 841-890) antibodyCEP152 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- CEP152 (Centrosomal Protein 152kDa (CEP152))
- 别名
- CEP152 (CEP152 产品)
- 别名
- AI851464 antibody, mKIAA0912 antibody, RGD1305348 antibody, MCPH4 antibody, MCPH9 antibody, SCKL5 antibody, centrosomal protein 152 antibody, CEP152 antibody, Cep152 antibody
- 背景
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Description: Necessary for centrosome duplication, the function seems also to involve CEP63, CDK5RAP2 and WDR62 through a stepwise assembled complex at the centrosome that recruits CDK2 required for centriole duplication (PubMed:26297806). Acts as a molecular scaffold facilitating the interaction of PLK4 and CENPJ, 2 Molecules involved in centriole formation (PubMed:21059844, PubMed:20852615). Proposed to snatch PLK4 away from PLK4:CEP92 complexes in early G1 daughter centriole and to reposition PLK4 at the outer boundary of a newly forming CEP152 ring structure (PubMed:24997597). Also plays a key role in deuterosome-mediated centriole amplification in multiciliated that can generate more than 100 centrioles (By similarity). Overexpression of CEP152 can drive amplification of centrioles (PubMed:20852615).
Gene: CEP152
- 分子量
- 140kDa
- 基因ID
- 22995
- UniProt
- O94986
- 途径
- M Phase
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