CEP152 抗体
Quick Overview for CEP152 抗体 (ABIN7112602)
抗原
See all CEP152 抗体适用
宿主
克隆类型
标记
应用范围
-
-
纯化方法
- Immunogen affinity purified
-
纯度
- ≥95 % as determined by SDS-PAGE
-
免疫原
- centrosomal protein 152kDa
-
亚型
- IgG
-
-
anti-Centrosomal Protein 152kDa (CEP152) (Internal Region) antibody
CEP152 适用: 人, 小鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Centrosomal Protein 152kDa (CEP152) (C-Term) antibodyCEP152 适用: 人 ELISA, WB, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Centrosomal Protein 152kDa (CEP152) (Internal Region) antibodyCEP152 适用: 人, 小鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Centrosomal Protein 152kDa (CEP152) (AA 841-890) antibodyCEP152 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB: 1:500-1:2000, IP: 1:200-1:1000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
-
有效期
- 12 months
-
-
- CEP152 (Centrosomal Protein 152kDa (CEP152))
-
别名
- CEP152
-
背景
- Synonyms:KIAA0912 Background:Necessary for centrosome duplication, the function seems also to involve CEP63, CDK5RAP2 and WDR62 through a stepwise assembled complex at the centrosome that recruits CDK2 required for centriole duplication(PubMed:26297806). Acts as a molecular scaffold facilitating the interaction of PLK4 and CENPJ, 2 Molecules involved in centriole formation(PubMed:21059844, PubMed:20852615). Proposed to snatch PLK4 away from PLK4:CEP92 complexes in early G1 daughter centriole and to reposition PLK4 at the outer boundary of a newly forming CEP152 ring structure(PubMed:24997597). Also plays a key role in deuterosome-mediated centriole amplification in multiciliated that can generate more than 100 centrioles(By similarity). Overexpression of CEP152 can drive amplification of centrioles(PubMed:20852615).
-
分子量
- 110 kDa
-
基因ID
- 22995
-
UniProt
- O94986
-
途径
- M Phase
抗原
-
